Description

2-(Trifluoromethyl)-1,3-thiazole-4-carboxylic acid is a high-value trifluoromethylated heterocyclic building block essential for modern synthetic chemistry. Its core value lies in the unique combination of the electron-withdrawing trifluoromethyl group and the versatile carboxylic acid functionality, enabling precise molecular modifications. This compound is primarily sought after by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting new small molecule therapeutics.
• Agrochemical Research: Used in the development of advanced pesticides and herbicides, where the trifluoromethyl group can enhance biological activity and metabolic stability.
• Ligand and Catalyst Synthesis: Serves as a precursor for creating specialized ligands or organocatalysts used in asymmetric synthesis and other catalytic processes.
• Material Science Building Block: Incorporated into advanced polymers or functional materials to impart specific electronic or surface properties.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects and scale-up activities.

Basic Information

Product Name	2-(Trifluoromethyl)-1,3-thiazole-4-carboxylic Acid
CAS No.	915030-08-9
Molecular Formula	C5H2F3NO2S
Molecular Weight	197.14 g/mol
Synonyms	4-Thiazolecarboxylic acid, 2-(trifluoromethyl)-; 2-(Trifluoromethyl)-4-thiazolecarboxylic acid; 2-Trifluoromethyl-1,3-thiazole-4-carboxylic acid; 2-Trifluoromethylthiazole-4-carboxylic acid; 4-Carboxy-2-(trifluoromethyl)thiazole; 915030-08-9
EINECS	Contact for details

Quality Control

Our 2-(Trifluoromethyl)-1,3-thiazole-4-carboxylic acid is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure consistency and compliance with research-grade standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.