Description

(2-Trifluoromethyl-Cyclopentyl)-Benzene is a specialized fluorinated aromatic compound that serves as a critical building block in advanced chemical synthesis. Its value lies in the unique combination of the robust benzene ring and the highly electronegative trifluoromethyl group, which can dramatically alter the physicochemical properties of target molecules. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors developing novel active ingredients with enhanced metabolic stability and bioavailability.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), particularly in CNS and antiviral drug candidates.
• Agrochemical Synthesis: Used in creating advanced herbicides and pesticides where the CF3 group improves lipophilicity and biological activity.
• Liquid Crystal & OLED Materials: Serves as a fluorinated core structure in the synthesis of electronic chemicals for display and lighting technologies.
• Advanced Polymer Modifiers: Incorporated as a monomer or additive to impart chemical resistance, thermal stability, and low surface energy to high-performance polymers.
• Catalyst Ligand Precursor: Utilized in organometallic chemistry to develop novel ligands for asymmetric catalysis and cross-coupling reactions.
• Fluorine-19 NMR Reference Standard: Acts as a calibration standard or chemical shift reference in analytical laboratories.

Basic Information

Product Name	(2-Trifluoromethyl-Cyclopentyl)-Benzene
CAS No.	914773-30-1
Molecular Formula	C12H13F3
Molecular Weight	214.23 g/mol
Synonyms	1-(2-Trifluoromethylcyclopentyl)benzene; Benzene, (2-(trifluoromethyl)cyclopentyl)-; α-(Trifluoromethyl)cyclopentylbenzene; 2-(Trifluoromethyl)cyclopentylbenzene; (2-(Trifluoromethyl)cyclopentyl)benzene; Cyclopentylbenzene, 2-trifluoromethyl-; 2-Trifluoromethyl-1-phenylcyclopentane
EINECS	Contact for details

Quality Control

Our (2-Trifluoromethyl-Cyclopentyl)-Benzene is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including GC, HPLC, NMR, and MS, to verify identity, potency, and impurity profiles. A Certificate of Analysis (COA) detailing all test results is provided with every shipment, ensuring full traceability and compliance with customer specifications and cGMP guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider maintaining the material under an inert atmosphere (e.g., nitrogen or argon) to preserve stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (GC)	≥ 97.0%
Purity (HPLC)	≥ 96.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.