Description

2-Benzenesulfonyl-5-(Trifluoromethyl)Benzaldehyde is a high-value, multi-functional aromatic aldehyde building block characterized by its benzenesulfonyl and trifluoromethyl substituents. This compound matters for its role as a critical intermediate in the synthesis of complex molecules, offering unique electronic and steric properties that influence reactivity and final product performance. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly in kinase inhibitor and anti-inflammatory research.
• Agrochemical Synthesis: Used in the development of advanced herbicides and fungicides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Material Science Research: Serves as a precursor for functionalized polymers and liquid crystals, leveraging its sulfonyl and aldehyde groups for polymerization or cross-linking.
• Organic Synthesis Reagent: Employed in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) and as an electrophile in nucleophilic addition reactions.
• Chemical Biology Probes: Useful for creating fluorescent tags or affinity probes due to the reactive aldehyde group for bioconjugation.

Basic Information

Product Name	2-Benzenesulfonyl-5-(Trifluoromethyl)Benzaldehyde
CAS No.	914637-53-9
Molecular Formula	C14H9F3O3S
Molecular Weight	314.28 g/mol
Synonyms	5-(Trifluoromethyl)-2-(phenylsulfonyl)benzaldehyde; 2-(Phenylsulfonyl)-5-(trifluoromethyl)benzaldehyde; [2-(Benzenesulfonyl)-5-(trifluoromethyl)phenyl]formaldehyde; Benzaldehyde, 2-(benzenesulfonyl)-5-(trifluoromethyl)-; 914637-53-9
EINECS	Contact for details

Quality Control

Our 2-Benzenesulfonyl-5-(Trifluoromethyl)Benzaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability, consistency, and reliability for your critical synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to handle and store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability, especially after opening the original container.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.