Description

Benzene, 1-Bromo-2,4-Difluoro-5-Iodo- is a highly functionalized halogenated benzene derivative, serving as a critical multi-functional building block in advanced organic synthesis. Its unique combination of bromo, fluoro, and iodo substituents on a single aromatic ring offers exceptional versatility for selective cross-coupling reactions and the introduction of complex molecular architectures. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and materials science industries who require precise, multi-step synthetic pathways.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring halogenated aromatic cores for bioactivity or further functionalization.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the difluoro and iodo groups contribute to metabolic stability and binding affinity.
• Liquid Crystal & OLED Materials: Serves as a building block for advanced electronic materials, where the halogen atoms influence molecular polarity and mesomorphic properties.
• Cross-Coupling Reactions: The bromo and iodo groups are excellent substrates for Suzuki, Stille, and Negishi couplings, allowing for sequential, selective derivatization.
• Fluorinated Compound Research: An important reagent for studying the effects of fluorine substitution in medicinal chemistry and material science.
• Chemical Reference Standard: Used for analytical method development and calibration in quality control laboratories.

Basic Information

Product Name	Benzene, 1-Bromo-2,4-Difluoro-5-Iodo-
CAS No.	914636-91-2
Molecular Formula	C6H2BrF2I
Molecular Weight	318.89 g/mol
Synonyms	1-Bromo-2,4-difluoro-5-iodobenzene; 2,4-Difluoro-5-iodo-1-bromobenzene; 5-Iodo-1-bromo-2,4-difluorobenzene; 1-Bromo-5-iodo-2,4-difluorobenzene; Benzene, bromodifluoroiodo-; (Bromo)(difluoro)(iodo)benzene
EINECS	Contact for details

Quality Control

Our Benzene, 1-Bromo-2,4-Difluoro-5-Iodo- is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and elemental analysis, to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided with each shipment, detailing all critical quality parameters. We support cGMP compliance for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.