Description

4-Fluoro-3-(Methylsulphonyl)Aniline is a high-purity, multi-functional aromatic amine building block of significant importance in advanced organic synthesis. Its unique structure, featuring both a fluorine substituent and a methylsulfonyl group, makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, including potential drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors, receptor antagonists, and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine and sulfonyl groups can enhance biological activity and environmental stability.
• Material Science Research: Serves as a monomer or functionalization agent in the development of specialty polymers, liquid crystals, and advanced organic electronic materials.
• Dye and Pigment Intermediate: Employed in the synthesis of complex, high-performance dyes and organic pigments due to its aniline core and electron-withdrawing substituents.
• Cross-Coupling Reactions: An essential substrate in palladium-catalyzed cross-coupling reactions (e.g., Buchwald-Hartwig amination, Suzuki-Miyaura) for creating complex biaryl and aryl amine structures.

Basic Information

Product Name	4-Fluoro-3-(Methylsulphonyl)Aniline
CAS No.	914636-44-5
Molecular Formula	C7H8FNO2S
Molecular Weight	189.21 g/mol
Synonyms	3-(Methylsulfonyl)-4-fluoroaniline; 4-Fluoro-3-(methylsulfonyl)benzenamine; 4-Fluoro-3-methanesulfonylaniline; Benzenamine, 4-fluoro-3-(methylsulfonyl)-; 4-Fluoro-3-methylsulphonylaniline
EINECS	Contact for details

Quality Control

Our 4-Fluoro-3-(Methylsulphonyl)Aniline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high chemical purity and consistency, meeting the stringent requirements for advanced synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to guarantee traceability and reliability for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This material is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere). Keep away from strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.