Description

Methyl 5,5,5-Trifluoro-4-(Phenylamino)Pent-3-Enoate is a high-value fluorinated building block and intermediate in advanced organic synthesis. This compound is critical for introducing the trifluoromethyl group and an enoate moiety into complex molecular architectures, enabling the development of novel compounds with enhanced properties. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing potential drug candidates, particularly those requiring trifluoromethylated motifs for improved metabolic stability and bioavailability.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides where the fluorine atoms can enhance biological activity and environmental persistence.
• Material Science Precursor: Serves as a monomer or intermediate for creating specialty polymers and advanced materials with unique surface properties.
• Chemical Synthesis Reagent: Employed in academic and industrial R&D for constructing complex organic molecules via Michael addition and other conjugate addition reactions.
• Fluorine Chemistry Studies: An important compound for investigating structure-activity relationships (SAR) and new fluorination methodologies in synthetic chemistry.

Basic Information

Product Name	Methyl 5,5,5-Trifluoro-4-(Phenylamino)Pent-3-Enoate
CAS No.	914613-27-7
Molecular Formula	C₁₃H₁₂F₃NO₂
Molecular Weight	271.24 g/mol
Synonyms	Methyl 5,5,5-trifluoro-4-(phenylamino)pent-3-enoate; 3-Pentenoic acid, 5,5,5-trifluoro-4-(phenylamino)-, methyl ester; Methyl (2E)-5,5,5-trifluoro-4-(phenylamino)pent-2-enoate; (E)-Methyl 5,5,5-trifluoro-4-(phenylamino)pent-3-enoate; 914613-27-7; Methyl 5,5,5-trifluoro-4-anilinopent-3-enoate
EINECS	Contact for details

Quality Control

Our Methyl 5,5,5-Trifluoro-4-(Phenylamino)Pent-3-Enoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent chemical identity. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Light yellow to yellow solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.