Description

4-(4-Methylpiperazin-1-Ylsulfonyl)Phenylboronic Acid Pinacol Ester is a high-purity, advanced pharmaceutical intermediate and versatile building block in organic synthesis. This compound is valued for its role in facilitating Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex biaryl structures. It is primarily utilized by research institutions and pharmaceutical companies engaged in the discovery and development of new active pharmaceutical ingredients (APIs), particularly within medicinal chemistry programs.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and oncology.
• Suzuki-Miyaura Cross-Coupling Reagent: Enables the formation of carbon-carbon bonds between aryl halides and boronic acids/esters, critical for creating complex molecular architectures.
• Medicinal Chemistry Research: Used in high-throughput screening and structure-activity relationship (SAR) studies to optimize lead compounds.
• Chemical Biology Probes: Serves as a precursor for synthesizing molecules used to study biological pathways and protein functions.
• Agrochemical Development: Employed in the research phase for creating new active ingredients with improved efficacy and selectivity.
• Material Science: Potential use in the synthesis of organic electronic materials and advanced polymers requiring specific aryl-aryl linkages.

Basic Information

Product Name	4-(4-Methylpiperazin-1-Ylsulfonyl)Phenylboronic Acid Pinacol Ester
CAS No.	914610-39-2
Molecular Formula	C18H29BN2O4S
Molecular Weight	380.31 g/mol
Synonyms	4-(4-Methyl-1-piperazinylsulfonyl)benzeneboronic acid pinacol ester; [4-(4-Methylpiperazine-1-sulfonyl)phenyl]boronic acid pinacol ester; 4-(N-Methylpiperazinylsulfonyl)phenylboronic acid pinacol ester; Pinacol 4-(4-Methylpiperazine-1-sulfonyl)phenylboronate; B-[4-[(4-Methyl-1-piperazinyl)sulfonyl]phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 914610-39-2 (CAS Index Name); 4-(4-Methylpiperazin-1-ylsulfonyl)phenylboronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 4-(4-Methylpiperazin-1-Ylsulfonyl)Phenylboronic Acid Pinacol Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged manipulations to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.