Description

3-(n-Cyclopropylaminocarbonyl)Phenylboronic Acid, Pinacol Ester is a sophisticated boronic ester derivative, a key building block in modern synthetic chemistry. Its value lies in its stability and reactivity, making it an essential intermediate for constructing complex molecular architectures. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for applications such as Suzuki-Miyaura cross-coupling reactions.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those requiring a cyclopropylamide-substituted phenylboronate moiety.
• Suzuki-Miyaura Cross-Coupling: Serves as a stable, air-handleable organoboron reagent for palladium-catalyzed carbon-carbon bond formation to create biaryl structures.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that incorporate specific aromatic boronic ester functionalities.
• Material Science Research: Employed in the development of organic electronic materials, such as polymers and small molecules for OLEDs or OFETs, where precise molecular structure is critical.
• Chemical Biology & Probe Development: Utilized as a synthetic handle for creating molecular probes and bioconjugates, leveraging boronic acid chemistry for sensing or targeting applications.

Basic Information

Product Name	3-(n-Cyclopropylaminocarbonyl)Phenylboronic Acid, Pinacol Ester
CAS No.	914397-31-2
Molecular Formula	C₁₆H₂₂BNO₃
Molecular Weight	287.17 g/mol
Synonyms	[3-(Cyclopropylcarbamoyl)phenyl]boronic acid pinacol ester; 3-(Cyclopropylaminocarbonyl)benzeneboronic acid pinacol ester; (3-(Cyclopropylcarbamoyl)phenyl)boronic acid pinacol ester; Pinacol 3-(Cyclopropylcarbamoyl)benzeneboronate; 3-Cyclopropylcarbamoylphenylboronic acid pinacol ester; B-[3-(Cyclopropylaminocarbonyl)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; CAS 914397-31-2
EINECS	Contact for details

Quality Control

Our production of 3-(n-Cyclopropylaminocarbonyl)Phenylboronic Acid, Pinacol Ester adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity for research and scale-up applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We are committed to supply chain reliability and full traceability for all our advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). This material is light-sensitive (store away from light). For long-term storage, consider under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.