Description

1-Boc-7-Nitro-3-Formylindole is a high-purity, multi-functional indole derivative, serving as a critical protected intermediate in advanced organic synthesis. Its value lies in providing a reactive formyl group and a protected amine, enabling precise and efficient construction of complex heterocyclic scaffolds. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active pharmaceutical ingredients (APIs) and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of complex indole-based drug candidates, including kinase inhibitors and receptor modulators.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators that leverage the indole core structure.
• Organic Synthesis: Serves as a versatile precursor for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) and other C-C bond-forming processes.
• Material Science: A potential monomer or intermediate for creating functional organic materials and dyes with specific electronic properties.
• Academic & Contract Research: Employed in medicinal chemistry programs and process development for scale-up synthesis.

Basic Information

Product Name	1-Boc-7-Nitro-3-Formylindole
CAS No.	914348-97-3
Molecular Formula	C₁₄H₁₄N₂O₅
Molecular Weight	290.27 g/mol
Synonyms	1-(tert-Butoxycarbonyl)-7-nitro-1H-indole-3-carboxaldehyde; tert-Butyl 7-nitro-3-formyl-1H-indole-1-carboxylate; 7-Nitro-1-Boc-indole-3-carboxaldehyde; 1-Boc-7-nitroindole-3-carbaldehyde; 1-Boc-7-NO2-3-CHO-indole; 1-Boc-7-nitro-3-formyl-1H-indole; 1-N-Boc-7-nitroindole-3-carboxaldehyde
EINECS	Contact for details

Quality Control

Our 1-Boc-7-Nitro-3-Formylindole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural integrity. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting compliance with research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This material is hygroscopic (moisture-sensitive) and easily oxidized; for long-term storage, consider storing under an inert atmosphere such as argon or nitrogen in a desiccated environment.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.