Description

2-(4-(Trifluoromethyl)Phenyl)Thiazole-5-Carbaldehyde is a high-purity, advanced pharmaceutical intermediate featuring a versatile thiazole core functionalized with a carbaldehyde group and a trifluoromethylphenyl moiety. This compound matters as a critical building block for synthesizing novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring enhanced metabolic stability and bioavailability. Pharmaceutical R&D laboratories and fine chemical manufacturers need this precise intermediate for developing new drugs, agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel small-molecule drugs, especially kinase inhibitors and anti-infective agents.
• Agrochemical Research: Used in the synthesis of new generation herbicides and fungicides, leveraging the bioactivity of the thiazole ring.
• Material Science: Serves as a precursor for organic ligands in catalysis and for creating functional polymers with specific electronic properties.
• Chemical Biology: Employed as a probe or labeling reagent due to its reactive aldehyde group for bioconjugation.
• Academic & Contract Research: Utilized in university and CRO laboratories for medicinal chemistry programs and structure-activity relationship (SAR) studies.

Basic Information

Product Name	2-(4-(Trifluoromethyl)Phenyl)Thiazole-5-Carbaldehyde
CAS No.	914348-80-4
Molecular Formula	C11H6F3NOS
Molecular Weight	257.23 g/mol
Synonyms	5-Formyl-2-[4-(trifluoromethyl)phenyl]thiazole; 2-[4-(Trifluoromethyl)phenyl]-1,3-thiazole-5-carboxaldehyde; 2-(4-Trifluoromethylphenyl)thiazole-5-carbaldehyde; 2-(4-(Trifluoromethyl)phenyl)-1,3-thiazole-5-carbaldehyde; 2-(4-Trifluoromethylphenyl)-5-formylthiazole; 5-Carbaldehyde-2-(4-trifluoromethylphenyl)thiazole; 914348-80-4; Thiazole-5-carbaldehyde, 2-[4-(trifluoromethyl)phenyl]-
EINECS	Contact for details

Quality Control

Our 2-(4-(Trifluoromethyl)Phenyl)Thiazole-5-Carbaldehyde is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.