Description

3-Bromo-2-Chlorobenzonitrile is a high-purity halogenated benzonitrile derivative, serving as a critical building block in advanced organic synthesis. Its value lies in providing a versatile molecular scaffold for constructing complex pharmacophores and functional materials. This intermediate is essential for research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific halogenated aromatic motifs into their target molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the bromo and chloro substituents modulate biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as semiconductors and liquid crystals, due to its electron-withdrawing nitrile group.
• Custom Synthesis and Contract Manufacturing: A valuable reagent for fine chemical companies offering bespoke synthesis services for client-specific molecular targets.
• Academic and R&D Laboratories: Utilized in methodological studies and the exploration of new cross-coupling and cyanation reactions.

Basic Information

Product Name	3-Bromo-2-Chlorobenzonitrile
CAS No.	914250-82-1
Molecular Formula	C7H3BrClN
Molecular Weight	216.46 g/mol
Synonyms	2-Chloro-3-bromobenzonitrile; 3-Bromo-2-chlorobenzene carbonitrile; 2-Chloro-3-bromobenzene nitrile; 3-Bromo-2-chloro-benzonitrile; Benzonitrile, 3-bromo-2-chloro-; (3-Bromo-2-chlorophenyl)carbonitrile
EINECS	Contact for details

Quality Control

Our 3-Bromo-2-Chlorobenzonitrile is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and industry best practices for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.