Description

4-Chloro-3-Nitrobenzeneboronic Acid, Pinacol Ester 98 is a high-purity, protected boronic acid derivative, a crucial building block in modern synthetic chemistry. Its primary value lies in enabling efficient and selective Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex biaryl and heterobiaryl structures. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries, facilitating the development of new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key synthon for constructing complex drug candidates, particularly those containing biphenyl or heterobiaryl scaffolds common in oncology, CNS, and antiviral therapies.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that require specific halogenated and nitrated aromatic systems.
• Material Science Research: Serves as a precursor for creating organic electronic materials, such as those used in OLEDs (Organic Light-Emitting Diodes) and OFETs (Organic Field-Effect Transistors).
• Ligand and Catalyst Development: Employed in the synthesis of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized to create tagged molecules for studying biological processes and protein interactions.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	4-Chloro-3-Nitrobenzeneboronic Acid, Pinacol Ester 98
CAS No.	913836-26-7
Molecular Formula	C12H15BClNO4
Molecular Weight	283.52 g/mol
Synonyms	4-Chloro-3-nitrophenylboronic acid pinacol ester; (4-Chloro-3-nitrophenyl)boronic acid pinacol ester; 2-(4-Chloro-3-nitrophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 4-Chloro-3-nitrobenzeneboronic acid pinanediol ester (common misnomer); 913836-26-7; Boronic acid, B-(4-chloro-3-nitrophenyl)-, 1,1-dimethylethyl ester; Pinacol (4-chloro-3-nitrophenyl)boronate
EINECS	Contact for details

Quality Control

Our 4-Chloro-3-Nitrobenzeneboronic Acid, Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure a minimum purity of 98% and conformity to specification. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent hydrolysis of the boronic ester.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.