Description

5-(Methylsulfonyl)-3-Pyridineboronic Acid is a high-purity boronic acid derivative featuring a pyridine core substituted with a methylsulfonyl group. This compound is a critical building block in modern synthetic chemistry, enabling the formation of carbon-carbon bonds via Suzuki-Miyaura cross-coupling reactions. It is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients. The product is supplied under stringent quality control to ensure batch-to-batch consistency for demanding R&D and scale-up processes.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small molecule therapeutics.
• Agrochemical Research: Used to construct complex heterocyclic scaffolds for new herbicides, fungicides, and plant growth regulators.
• Material Science: Building block for creating functionalized polymers, ligands for catalysis, and organic electronic materials.
• Chemical Synthesis: Versatile reagent for Suzuki-Miyaura cross-coupling reactions to introduce the 5-(methylsulfonyl)-3-pyridyl moiety into target molecules.
• Bioconjugation & Probe Development: Useful in medicinal chemistry for creating bioconjugates or molecular probes due to its reactive boronic acid group.

Basic Information

Product Name	5-(Methylsulfonyl)-3-Pyridineboronic Acid
CAS No.	913836-01-8
Molecular Formula	C7H10BNO4S
Molecular Weight	215.03 g/mol
Synonyms	(5-Methylsulfonylpyridin-3-yl)boronic Acid; 3-Pyridineboronic Acid, 5-(Methylsulfonyl)-; 5-Methanesulfonylpyridine-3-boronic Acid; 5-(Methylsulfonyl)-3-pyridinylboronic Acid; 913836-01-8; Boronic acid, B-[5-(methylsulfonyl)-3-pyridinyl]-
EINECS	Contact for details

Quality Control

Our 5-(Methylsulfonyl)-3-Pyridineboronic Acid is manufactured under a cGMP-compliant quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.