Description

4-Boronobenzenesulfonic Acid is a versatile organoboron building block featuring both a boronic acid and a sulfonic acid functional group on an aromatic ring. This unique bifunctional structure makes it a critical intermediate for synthesizing complex molecules in advanced material science and pharmaceutical research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications such as Suzuki-Miyaura cross-coupling and the creation of functionalized polymers or metal-organic frameworks.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in Suzuki-Miyaura cross-coupling reactions for constructing biaryl structures found in active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides that require boronic acid and sulfonate functionalities.
• Material Science: Acts as a monomer or cross-linking agent for creating sulfonated polymers, ion-exchange resins, and advanced porous materials like MOFs (Metal-Organic Frameworks).
• Chemical Biology & Proteomics: Employed in the synthesis of affinity probes, enzyme inhibitors, and bioconjugation reagents leveraging its dual reactive sites.
• Catalyst & Ligand Development: Utilized to synthesize novel sulfonated ligands for transition metal catalysis, enhancing catalyst solubility and activity in aqueous media.
• Dye & Pigment Manufacturing: Functions as an intermediate for producing sulfonated aromatic dyes and pigments with improved water solubility and fastness properties.

Basic Information

Product Name	4-Boronobenzenesulfonic Acid
CAS No.	913836-00-7
Molecular Formula	C6H7BO5S
Molecular Weight	201.99 g/mol
Synonyms	Benzenesulfonic acid, 4-borono-; p-Boronobenzenesulfonic Acid; 4-Sulfophenylboronic Acid; (4-Sulfophenyl)boronic Acid; B-(4-Sulfophenyl)boronic Acid; 4-Borono-1-sulfobenzene; p-Sulfophenylboronic Acid; 4-Boronobenzene-1-sulfonic Acid
EINECS	Contact for details

Quality Control

Our 4-Boronobenzenesulfonic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 95.0% (as C6H7BO5S)
Water Content (KF)	≤ 2.0%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.