Description

1-(tert-Butoxycarbonyl)-7-Methoxy-1H-Indol-2-Ylboronic Acid is a high-purity, advanced pharmaceutical intermediate designed for complex organic synthesis. This compound is a critical building block in modern medicinal chemistry, valued for its role in facilitating key carbon-carbon bond-forming reactions. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for constructing biaryl and heterobiaryl structures in drug discovery.
• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of complex indole-based drug candidates.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies for new therapeutic agents.
• Process Chemistry Development: Employed in scaling up synthetic routes for potential Active Pharmaceutical Ingredients (APIs).
• Fine Chemical Synthesis: Applied in the production of specialized agrochemicals and advanced materials.

Basic Information

Product Name	1-(tert-Butoxycarbonyl)-7-Methoxy-1H-Indol-2-Ylboronic Acid
CAS No.	913835-81-1
Molecular Formula	C₁₄H₁₈BNO₅
Molecular Weight	291.11 g/mol
Synonyms	7-Methoxy-1-Boc-indole-2-boronic acid; 1-Boc-7-Methoxy-1H-indole-2-boronic acid; 1-(tert-Butoxycarbonyl)-7-methoxy-1H-indole-2-boronic acid; 2-Borono-7-methoxy-1H-indole-1-carboxylic acid tert-butyl ester; tert-Butyl 7-methoxy-2-borono-1H-indole-1-carboxylate; 1H-Indole-2-boronic acid, 1-[(1,1-dimethylethoxy)carbonyl]-7-methoxy-; Boc-7-MeO-indole-2-B(OH)₂
EINECS	Contact for details

Quality Control

Our 1-(tert-Butoxycarbonyl)-7-Methoxy-1H-Indol-2-Ylboronic Acid is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is analyzed using advanced techniques such as HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability. For long-term storage, consider storing desiccated at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.