Description

3-Fluoro-4-[(4-Methoxybenzyloxy)Carbonylamino]Benzeneboronic Acid 98 is a high-purity, organoboron building block of significant interest in modern synthetic chemistry. Its core value lies in its dual functionality, combining a boronic acid group for Suzuki-Miyaura cross-coupling reactions with a protected amino acid derivative, enabling the synthesis of complex, fluorinated bioactive molecules. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries who are developing new active ingredients, particularly protease inhibitors and other targeted therapies.

Application

• Pharmaceutical Intermediate: A key synthon for the construction of fluorinated peptide mimetics and protease inhibitor candidates.
• Suzuki-Miyaura Cross-Coupling: Serves as a versatile boronic acid partner for palladium-catalyzed C-C bond formation to create biaryl structures.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to introduce fluorine and specific side-chain motifs.
• Agrochemical Synthesis: Building block for novel, fluorinated herbicides and fungicides with enhanced activity and environmental profile.
• Chemical Biology Probes: Facilitates the synthesis of activity-based probes for studying enzyme function and target engagement.
• Material Science: Potential monomer or precursor for advanced polymeric materials with specific electronic or binding properties.

Basic Information

Item	Detail
Product Name	3-Fluoro-4-[(4-Methoxybenzyloxy)Carbonylamino]Benzeneboronic Acid 98
CAS No.	913835-49-1
Molecular Formula	C16H17BFNO5
Molecular Weight	333.12 g/mol
Synonyms	3-Fluoro-4-[[(4-methoxyphenyl)methoxy]carbonylamino]benzeneboronic acid; 4-[[(4-Methoxybenzyl)oxy]carbonylamino]-3-fluorobenzeneboronic acid; 3-Fluoro-4-[(4-methoxybenzyloxy)carbonylamino]phenylboronic acid; 3-Fluoro-4-(PMB-oxycarbonylamino)benzeneboronic acid; 3-Fluoro-4-(N-PMB-oxycarbonylamino)phenylboronic acid; 913835-49-1; 4-(N-[(4-Methoxybenzyl)oxy]carbonylamino)-3-fluorophenylboronic acid
EINECS	Contact for details

Quality Control

Our 3-Fluoro-4-[(4-Methoxybenzyloxy)Carbonylamino]Benzeneboronic Acid 98 is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure compliance with exacting standards for research and development. Certificates of Analysis (COA) documenting the specific results are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and when dispensing to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.