Description

4-(3-Chloro-4-Methylphenylcarbamoyl)Phenylboronic Acid is a high-purity, functionalized boronic acid derivative designed for advanced synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the precise construction of complex molecular architectures. It is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, especially in kinase inhibitor and oncology research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, leveraging its boronic acid functionality for carbon-carbon bond formation.
• Material Science Research: Employed in the creation of organic electronic materials, such as polymers and small molecules for OLEDs and sensors.
• Chemical Biology: Acts as a versatile handle for bioconjugation and the synthesis of probes for studying biological processes.
• Catalyst Ligand Development: The structural motif can be utilized in designing novel ligands for transition metal catalysis.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and complex targets under cGMP conditions where required.

Basic Information

Product Name	4-(3-Chloro-4-Methylphenylcarbamoyl)Phenylboronic Acid
CAS No.	913835-37-7
Molecular Formula	C14H13BClNO3
Molecular Weight	289.52 g/mol
Synonyms	[4-[(3-Chloro-4-methylphenyl)carbamoyl]phenyl]boronic acid; 4-Carbamoylphenylboronic acid, 3-chloro-4-methyl derivative; B-[4-[[(3-Chloro-4-methylphenyl)amino]carbonyl]phenyl]boronic acid; 4-(3-Chloro-4-methylbenzamido)benzeneboronic acid; 913835-37-7; (4-((3-Chloro-4-methylphenyl)carbamoyl)phenyl)boronic acid
EINECS	Contact for details

Quality Control

Our 4-(3-Chloro-4-Methylphenylcarbamoyl)Phenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with full traceability are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.