Description

(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Boronic Acid is a high-purity, protected boronic acid derivative that serves as a critical building block in advanced organic synthesis. Its primary value lies in its enhanced stability compared to many free boronic acids, making it an essential reagent for demanding cross-coupling reactions. This compound is particularly vital for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries who require reliable, high-quality intermediates for complex molecule construction.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key precursor for forming carbon-carbon bonds in the synthesis of complex biaryl structures, a common motif in active pharmaceutical ingredients (APIs) and advanced materials.
• Pharmaceutical Intermediate Synthesis: Used in the research and production of drug candidates, especially where the stability of the boronic ester moiety is advantageous over the free acid.
• Agrochemical Development: Employed in creating novel herbicides, fungicides, and insecticides that require specific aryl or heteroaryl components.
• Ligand and Catalyst Preparation: Serves as a starting material for synthesizing specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Materials Science Research: Utilized in the development of organic electronic materials, such as those for OLEDs and semiconductors, where precise molecular architecture is crucial.
• Chemical Biology & Proteomics: Acts as a handle for bioconjugation and labeling strategies due to its selective reactivity.

Basic Information

Product Name	(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Boronic Acid
CAS No.	913739-28-3
Molecular Formula	C6H14B2O4
Molecular Weight	171.80 g/mol
Synonyms	2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)boronic acid; Pinacol Boronic Acid Ester; Pinacol Boronate; 2-Borono-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; Pinacolato Boronic Acid; (Pinacolato)Boronic Acid; B-Boronopinacol ester; Tetramethyl-1,3,2-dioxaborolane-2-boronic acid
EINECS	Contact for details

Quality Control

Our (4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Boronic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency suitable for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged manipulations to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.