Description

3,4,5-Trifluorobenzenesulfonamide is a high-value fluorinated aromatic sulfonamide building block. This compound is critical for introducing specific steric and electronic properties into target molecules, enabling advanced material and pharmaceutical development. It is primarily sought after by researchers and process chemists in the pharmaceutical, agrochemical, and specialty materials industries for the synthesis of novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A key synthon in the development of new drug candidates, particularly for kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides with improved efficacy and environmental profiles.
• Material Science: Serves as a monomer or additive in the synthesis of specialty polymers, such as sulfonated poly(arylene ether sulfone)s for membrane applications.
• Ligand and Catalyst Development: Employed in the design of novel ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Research: A versatile building block for organic synthesis, enabling the exploration of new chemical space in medicinal and materials chemistry.

Basic Information

Product Name	3,4,5-Trifluorobenzenesulfonamide
CAS No.	913472-55-6
Molecular Formula	C6H4F3NO2S
Molecular Weight	211.16 g/mol
Synonyms	Benzenesulfonamide, 3,4,5-trifluoro-; 3,4,5-Trifluorobenzene-1-sulfonamide; 3,4,5-Trifluorophenylsulfonamide; 3,4,5-Trifluoro-benzenesulfonic acid amide; 913472-55-6; 3,4,5-Trifluorobenzenesulfonic acid amide
EINECS	Contact for details

Quality Control

Our 3,4,5-Trifluorobenzenesulfonamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.