Description

1H-Indole-1-Carboxylic Acid, 2-Borono-5-[3-(Dimethylamino)Propyl]-, 1-(1,1-Dimethylethyl) Ester is a sophisticated boronic acid ester derivative of indole, serving as a critical building block in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of pharmaceuticals and complex bioactive molecules, particularly where precise molecular architecture is required. It is primarily needed by research institutions and pharmaceutical companies engaged in drug discovery, medicinal chemistry, and the synthesis of novel chemical entities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and investigational new drugs.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and the development of novel therapeutic agents, particularly in oncology and CNS disorders.
• Suzuki-Miyaura Cross-Coupling Reactions: Functions as a versatile boronic ester coupling partner for constructing complex biaryl and heterobiaryl structures.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Agrochemical Research: Serves as an intermediate in the development of new crop protection agents and pesticides.
• Material Science: Potential building block for advanced organic electronic materials and functional polymers.

Basic Information

Product Name	1H-Indole-1-Carboxylic Acid, 2-Borono-5-[3-(Dimethylamino)Propyl]-, 1-(1,1-Dimethylethyl) Ester
CAS No.	913388-76-8
Molecular Formula	C20H31BN2O4
Molecular Weight	374.29 g/mol
Synonyms	2-Borono-5-[3-(dimethylamino)propyl]-1H-indole-1-carboxylic acid 1,1-dimethylethyl ester; tert-Butyl 2-borono-5-[3-(dimethylamino)propyl]-1H-indole-1-carboxylate; 5-[3-(Dimethylamino)propyl]-1H-indole-2-boronic acid tert-butyl ester; Boronic acid, B-[5-[3-(dimethylamino)propyl]-1-[(1,1-dimethylethoxy)carbonyl]-1H-indol-2-yl]-, (T-4)-; CAS 913388-76-8
EINECS	Contact for details

Quality Control

Our 1H-Indole-1-Carboxylic Acid, 2-Borono-5-[3-(Dimethylamino)Propyl]-, 1-(1,1-Dimethylethyl) Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) in its original sealed packaging to prevent degradation. For long-term storage, consider storing at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.