Description

1H-Indole-1-Carboxylic Acid, 2-Borono-5-[2-(4-Morpholinyl)Ethoxy]-, 1-(1,1-Dimethylethyl) Ester is a sophisticated boronic acid ester derivative, serving as a critical building block in modern synthetic chemistry. Its value lies in its dual functionality, combining a protected boronic acid moiety with an indole core and a morpholinoethoxy side chain, enabling precise cross-coupling reactions and targeted molecular construction. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and complex organic molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and oncology.
• Suzuki-Miyaura Cross-Coupling Reactions: Acts as a versatile boronate ester coupling partner for constructing biaryl and heterobiaryl structures under mild conditions.
• Agrochemical Research: Used in the development of new pesticides and herbicides with specific modes of action.
• Material Science: Employed in the synthesis of organic electronic materials and advanced polymers.
• Chemical Biology Probes: Facilitates the creation of labeled compounds and probes for studying biological pathways.
• Process Chemistry Development: Serves as a high-value intermediate for scaling up the production of complex target molecules.

Basic Information

Product Name	1H-Indole-1-Carboxylic Acid, 2-Borono-5-[2-(4-Morpholinyl)Ethoxy]-, 1-(1,1-Dimethylethyl) Ester
CAS No.	913388-60-0
Molecular Formula	C19H27BN2O5
Molecular Weight	374.24 g/mol
Synonyms	2-Borono-5-[2-(4-morpholinyl)ethoxy]-1H-indole-1-carboxylic acid 1,1-dimethylethyl ester; tert-Butyl 2-borono-5-(2-morpholinoethoxy)-1H-indole-1-carboxylate; 5-(2-Morpholin-4-yl-ethoxy)-1H-indole-1-carboxylic acid tert-butyl ester 2-boronic acid; Boronate Ester Intermediate 913388-60-0; BOC-protected Indole Boronic Acid Ester; CAS 913388-60-0.
EINECS	Contact for details

Quality Control

Our production of 1H-Indole-1-Carboxylic Acid, 2-Borono-5-[2-(4-Morpholinyl)Ethoxy]-, 1-(1,1-Dimethylethyl) Ester adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and Karl Fischer titration for moisture content, to ensure it meets the exacting standards required for research and process chemistry. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; prolonged exposure to air, moisture, or light should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.