Description

1H-Indole-1-Carboxylic Acid, 2-Borono-5-Formyl-, 1-(1,1-Dimethylethyl) Ester is a sophisticated boronic acid ester derivative of indole, serving as a high-value synthetic intermediate in advanced organic chemistry. Its core value lies in enabling precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone of modern pharmaceutical and materials science research. This compound is essential for medicinal chemists and process R&D teams developing novel active pharmaceutical ingredients (APIs), agrochemicals, and functional organic materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of complex indole-based drug candidates targeting neurological disorders, oncology, and inflammation.
• Agrochemical Research: Used in creating novel herbicides, fungicides, and plant growth regulators with enhanced efficacy and selectivity.
• Material Science: Precursor for organic electronic materials, including OLEDs (Organic Light-Emitting Diodes) and conductive polymers.
• Chemical Biology & Proteomics: Serves as a versatile handle for bioconjugation and the development of molecular probes and inhibitors.
• Catalyst & Ligand Development: Employed in the design of novel organometallic catalysts and chiral ligands for asymmetric synthesis.
• Academic & Contract Research: Critical reagent for methodology development and exploring new synthetic pathways in academic and CRO (Contract Research Organization) laboratories.

Basic Information

Item	Details
Product Name	1H-Indole-1-Carboxylic Acid, 2-Borono-5-Formyl-, 1-(1,1-Dimethylethyl) Ester
CAS No.	913388-54-2
Molecular Formula	C16H20BNO5
Molecular Weight	317.15 g/mol
Synonyms	2-Borono-5-formyl-1H-indole-1-carboxylic acid 1,1-dimethylethyl ester; tert-Butyl 2-borono-5-formyl-1H-indole-1-carboxylate; 5-Formyl-1H-indole-2-boronic acid tert-butyl ester; 2-Boron-5-formyl-1H-indole-1-carboxylic acid tert-butyl ester; Boronic acid, B-(5-formyl-1-[[(1,1-dimethylethoxy)carbonyl]-1H-indol-2-yl]-; CAS 913388-54-2
EINECS	Contact for details

Quality Control

Every batch of 1H-Indole-1-Carboxylic Acid, 2-Borono-5-Formyl-, 1-(1,1-Dimethylethyl) Ester is produced and tested under strict quality management systems to ensure high purity, lot-to-lot consistency, and reliable performance in sensitive coupling reactions. Our products undergo rigorous quality testing, including HPLC, NMR, and elemental analysis, to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) due to its hygroscopic and moisture-sensitive nature. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.