Description

Propanimidic Acid, 3,3,3-Trifluoro-2-Hydroxy-, Ethyl Ester is a specialized fluorinated organic building block of significant interest in advanced chemical synthesis. This compound matters for its role as a key intermediate in the development of pharmaceuticals and agrochemicals, where its unique trifluoromethyl and hydroxyimidate functionalities enable the construction of complex, bioactive molecules. Industries such as pharmaceutical R&D, agrochemical manufacturing, and fine chemical production need this high-purity intermediate to drive innovation in new active ingredient development.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Fluorinated Building Block: Serves as a versatile reagent for introducing the CF3 group into complex organic molecules in medicinal and materials chemistry.
• Ligand and Catalyst Development: Employed in the creation of specialized ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Fine Chemical Production: Utilized in custom synthesis and contract manufacturing for high-value, low-volume specialty chemicals.
• Research & Development: Essential for academic and industrial R&D labs exploring new synthetic methodologies and fluorine chemistry.

Basic Information

Product Name	Propanimidic Acid, 3,3,3-Trifluoro-2-Hydroxy-, Ethyl Ester
CAS No.	912756-54-8
Molecular Formula	C5H6F3NO2
Molecular Weight	169.10 g/mol
Synonyms	Ethyl 3,3,3-trifluoro-2-hydroxypropanimidate; 2-Hydroxy-3,3,3-trifluoropropanimidic Acid Ethyl Ester; 3,3,3-Trifluoro-2-hydroxypropanimidic acid ethyl ester; Trifluorolactic acid imidate ethyl ester; Ethyl trifluorolactimidate; TFLEI; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our Propanimidic Acid, 3,3,3-Trifluoro-2-Hydroxy-, Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. This material is sensitive to moisture and strong bases; keep the container tightly sealed under an inert atmosphere such as nitrogen or argon to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.