Description

4,4,5,5-Tetramethyl-2-[2-(Phenoxymethyl)Phenyl]-1,3,2-Dioxaborolane is a high-purity, advanced boronic ester building block essential for modern synthetic chemistry. Its core value lies in enabling efficient, high-yielding cross-coupling reactions, which are fundamental to constructing complex molecular architectures. This compound is critically needed by researchers and process chemists in the pharmaceutical, agrochemical, and materials science industries for developing new active ingredients and functional polymers.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds between aryl/heteroaryl groups, crucial in medicinal chemistry.
• Pharmaceutical Intermediate Synthesis: Used in the research and development of novel Active Pharmaceutical Ingredients (APIs) and drug candidates.
• Agrochemical Development: Serves as a building block for creating new herbicides, fungicides, and insecticides with improved efficacy.
• Organic Light-Emitting Diode (OLED) Materials: A precursor in the synthesis of advanced organic electronic materials and emissive layers.
• Ligand and Catalyst Design: Employed in the preparation of novel ligands for transition metal catalysis and organoboron catalysts.
• Polymer and Material Science: Used to incorporate boronate functional groups into polymers for sensors, self-healing materials, or controlled release systems.
• Chemical Biology & Bioconjugation: Facilitates the site-specific labeling and modification of biomolecules for research and diagnostic applications.

Basic Information

Product Name	4,4,5,5-Tetramethyl-2-[2-(Phenoxymethyl)Phenyl]-1,3,2-Dioxaborolane
CAS No.	912569-55-2
Molecular Formula	C21H25BO3
Molecular Weight	336.24 g/mol
Synonyms	2-[2-(Phenoxymethyl)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; [2-(Phenoxymethyl)phenyl]boronic acid pinacol ester; (2-(Phenoxymethyl)phenyl)boronic acid pinacol ester; 2-(2-Phenoxymethylphenyl)-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane; 2-(2-(Phenoxymethyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; Boronic acid, B-[2-(phenylmethoxy)phenyl]-, 1,1-dimethylethyl ester; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 4,4,5,5-Tetramethyl-2-[2-(Phenoxymethyl)Phenyl]-1,3,2-Dioxaborolane is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for sensitive applications. Each lot undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent hydrolysis and maintain optimal reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5% w/w
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.