Description

Propargyl 2,3,4-Tri-o-Acetyl-α-L-Fucopyranoside is a high-purity, synthetically derived glycoside building block, specifically a protected derivative of L-fucose. This compound is a critical intermediate for the synthesis of complex oligosaccharides and glycoconjugates, enabling precise chemical modifications. It is primarily utilized by research institutions and pharmaceutical companies engaged in carbohydrate chemistry, glycobiology research, and the development of novel therapeutics and diagnostic tools.

Application

• Glycoconjugate Synthesis: A key protected intermediate for constructing complex carbohydrate structures linked to proteins, lipids, or other aglycons.
• Oligosaccharide Assembly: Used in chemical and chemoenzymatic strategies to build specific fucose-containing oligosaccharides for biological studies.
• Pharmaceutical Research: Serves as a precursor in the development of carbohydrate-based drugs, vaccines, and diagnostic agents.
• Chemical Biology Probes: The propargyl group allows for further functionalization via click chemistry (e.g., CuAAC), enabling the creation of labeled glycans for imaging or pull-down assays.
• Enzyme Substrate Studies: Used to study the activity and specificity of glycosyltransferases, glycosidases, and other carbohydrate-processing enzymes.
• Material Science: Potential use in creating functionalized surfaces or polymers with specific carbohydrate motifs for biosensing or biocompatibility applications.

Basic Information

Product Name	Propargyl 2,3,4-Tri-o-Acetyl-α-L-Fucopyranoside
CAS No.	912343-81-8
Molecular Formula	C₁₅H₂₀O₈
Molecular Weight	328.32 g/mol
Synonyms	Propargyl 2,3,4-Tri-O-acetyl-α-L-fucopyranoside; 1-O-Propargyl-2,3,4-tri-O-acetyl-α-L-fucopyranose; α-L-Fucopyranoside, propargyl 2,3,4-tri-O-acetyl-; Propargyl tri-O-acetyl-α-L-fucopyranoside; 2,3,4-Tri-O-acetyl-α-L-fucopyranosyl propargyl ether; (2R,3S,4S,5R,6S)-2-(Acetyloxymethyl)-6-(prop-2-yn-1-yloxy)tetrahydro-2H-pyran-3,4,5-triyl triacetate
EINECS	Contact for details

Quality Control

Our Propargyl 2,3,4-Tri-o-Acetyl-α-L-Fucopyranoside is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity, suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for fine chemical production, and custom synthesis and purification to meet specific project requirements are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed in a desiccated environment. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.