Description

6-Methyl-1H-Indole-2-Boronic Acid Pinacol Ester is a high-purity, protected boronic acid derivative essential for modern synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the efficient construction of complex indole-based molecular architectures. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for drug discovery and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly those containing functionalized indole scaffolds.
• Agrochemical Research: Used in the development of new active ingredients for crop protection products, leveraging the indole moiety's bioactivity.
• Material Science: Employed in the synthesis of organic electronic materials, such as OLEDs and conductive polymers, where precise molecular structure is paramount.
• Chemical Biology: Acts as a versatile handle for bioconjugation and the synthesis of molecular probes for biological target identification.
• Catalyst & Ligand Development: Serves as a starting material for creating novel ligands and organometallic catalysts used in asymmetric synthesis.
• Academic & Contract Research: A valuable reagent for methodology development and library synthesis in academic and contract research organizations (CROs).

Basic Information

Item	Details
Product Name	6-Methyl-1H-Indole-2-Boronic Acid Pinacol Ester
CAS No.	912332-45-7
Molecular Formula	C₁₅H₂₀BNO₂
Molecular Weight	257.14 g/mol
Synonyms	6-Methyl-1H-indol-2-ylboronic acid pinacol ester; 2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-6-methyl-1H-indole; 6-Methylindole-2-boronic acid pinacol ester; 6-Methyl-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole; Pinacol 6-Methyl-1H-indole-2-boronate
EINECS	Contact for details

Quality Control

Every batch of 6-Methyl-1H-Indole-2-Boronic Acid Pinacol Ester is manufactured under strict quality management systems and undergoes comprehensive analytical testing. We ensure compliance with stringent internal specifications for identity, purity, and impurity profiles. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming key parameters such as assay (by HPLC/NMR) and levels of critical impurities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The product is light-sensitive (store away from light). Keep the container tightly sealed under an inert atmosphere to maintain stability and prevent moisture uptake.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥97.0%
Purity (NMR)	Conforms
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.