Description

(E)-5-Fluoro-3,4-Dihydronaphthalen-1(2H)-One Oxime is a high-purity, fluorinated oxime derivative with a defined stereochemistry. This compound serves as a critical advanced pharmaceutical intermediate and a versatile building block in organic synthesis. It is primarily utilized by research institutions and chemical manufacturers in the pharmaceutical and agrochemical sectors for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of fluorinated drug candidates, particularly for central nervous system (CNS) and oncology targets.
• Agrochemical Research: Building block for developing new-generation herbicides and pesticides with enhanced efficacy and selectivity.
• Organic Synthesis Reagent: Used in cyclization reactions and as a nucleophile or electrophile in constructing complex heterocyclic frameworks.
• Material Science Research: Potential monomer or additive in the development of specialty polymers and advanced materials.
• Chemical Reference Standard: High-purity grade for analytical method development, validation, and quality control in regulatory submissions.

Basic Information

Product Name	(E)-5-Fluoro-3,4-Dihydronaphthalen-1(2H)-One Oxime
CAS No.	911825-56-4
Molecular Formula	C10H10FNO2
Molecular Weight	195.19 g/mol
Synonyms	(E)-5-Fluoro-1,2,3,4-tetrahydronaphthalen-1-one oxime; 5-Fluoro-3,4-dihydro-1(2H)-naphthalenone oxime; (E)-5-Fluoro-α-tetralone oxime; 5-Fluoro-α-tetralone oxime; 911825-56-4; (E)-5-Fluoro-1-oxo-1,2,3,4-tetrahydronaphthalen-1-ol oxime
EINECS	Contact for details

Quality Control

Our (E)-5-Fluoro-3,4-Dihydronaphthalen-1(2H)-One Oxime is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided with every shipment, detailing all relevant specifications. We support development and commercial projects requiring compliance with cGMP and ICH Q7 guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong alkalis and sources of fluoride ions. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.