Description

2H-1-Benzopyran-3-Carboxaldehyde, 6-Methoxy-2-Phenyl-, (2R)- is a high-purity, single-enantiomer chiral building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of optically active pharmaceuticals and fine chemicals, where stereochemical control is critical. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to construct complex molecular architectures with high enantiomeric purity.

Application

• Pharmaceutical Intermediate: A crucial chiral precursor for the synthesis of potential drug candidates, particularly in therapeutic areas requiring specific stereochemistry.
• Asymmetric Synthesis: Employed as a building block in catalytic asymmetric reactions to introduce the benzopyran scaffold with defined (R)-configuration.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs for novel bioactive molecules.
• Agrochemical Development: Serves as an intermediate in the research and synthesis of chiral active ingredients for crop protection agents.
• Material Science: Investigated as a monomer or precursor for creating chiral polymers or advanced organic materials with specific optical properties.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic chemistry and for exploring new synthetic pathways.

Basic Information

Item	Detail
Product Name	2H-1-Benzopyran-3-Carboxaldehyde, 6-Methoxy-2-Phenyl-, (2R)-
CAS No.	911107-23-8
Molecular Formula	C17H14O3
Molecular Weight	266.29 g/mol
Synonyms	(R)-6-Methoxy-2-phenyl-2H-chromene-3-carbaldehyde; (2R)-6-Methoxy-2-phenyl-2H-1-benzopyran-3-carboxaldehyde; (R)-6-Methoxy-2-phenylchromene-3-carboxaldehyde; (R)-Flavan-3-carboxaldehyde derivative; (R)-2-Phenyl-6-methoxychromone-3-carboxaldehyde (tautomeric form); (R)-PMC Aldehyde; (R)-2H-Chromene-3-carboxaldehyde, 6-methoxy-2-phenyl-
EINECS	Contact for details

Quality Control

Our 2H-1-Benzopyran-3-Carboxaldehyde, 6-Methoxy-2-Phenyl-, (2R)- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric excess (ee) verification, to ensure it meets the high-purity standards required for sensitive synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and chiral purity are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is light-sensitive and should be stored away from direct light. For long-term storage, consider storing under an inert atmosphere to minimize potential oxidation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.