Description

2-Methyl-3-Nitrophenylboronic Acid, Pinacol Ester is a high-purity, organoboron building block essential for modern synthetic chemistry. This compound is a protected boronic acid derivative, offering enhanced stability and handling characteristics for complex coupling reactions. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced materials.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for constructing biaryl and heterobiaryl scaffolds prevalent in drug discovery.
• Pharmaceutical Intermediate Synthesis: Used in the research and development of potential therapeutic agents, including kinase inhibitors and other small molecule drugs.
• Agrochemical Research: Serves as a building block for creating novel herbicides, fungicides, and insecticides with specific activity profiles.
• Material Science & OLED Development: Employed in the synthesis of organic semiconductors, ligands for catalysts, and emissive materials for electronic devices.
• Chemical Biology & Probe Development: Useful for creating molecular probes and tagged compounds for studying biological systems.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring specific, functionalized aromatic boronic esters.

Basic Information

Product Name	2-Methyl-3-Nitrophenylboronic Acid, Pinacol Ester
CAS No.	910235-64-2
Molecular Formula	C13H18BNO4
Molecular Weight	263.10 g/mol
Synonyms	2-Methyl-3-nitrophenylboronic acid pinacol ester; (2-Methyl-3-nitrophenyl)boronic acid pinacol ester; 2-Methyl-3-nitrobenzeneboronic acid pinacol ester; 4,4,5,5-Tetramethyl-2-(2-methyl-3-nitrophenyl)-1,3,2-dioxaborolane; Pinacol (2-methyl-3-nitrophenyl)boronate; B-(2-Methyl-3-nitrophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
EINECS	Contact for details

Quality Control

Every batch of our 2-Methyl-3-Nitrophenylboronic Acid, Pinacol Ester is produced and tested under a strict quality management system. We ensure high lot-to-lot consistency and purity to meet the exacting standards of research and process chemistry. Comprehensive analytical testing, including HPLC, NMR, and GC, is performed. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to protect from moisture. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.