Description

4-Methyl-3,4-dihydro-2H-pyrido[3,2-b][1,4]oxazine-7-boronic acid, pinacol ester is a sophisticated heterocyclic boronic ester building block, essential for modern synthetic chemistry. Its core value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a pivotal method for constructing complex carbon-carbon bonds under mild conditions. This high-purity intermediate is primarily needed by pharmaceutical R&D and agrochemical laboratories for the discovery and development of novel active compounds.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) therapeutic research.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Material Science Research: Serves as a precursor for creating organic electronic materials, such as novel polymers or small molecules for OLEDs and sensors.
• Chemical Biology Probes: Enables the synthesis of tagged molecules for studying biological pathways and protein interactions.
• Catalyst Ligand Development: Can be utilized to create novel ligand frameworks for transition metal catalysis.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses serving the life sciences industry.

Basic Information

Product Name	4-Methyl-3,4-dihydro-2H-pyrido[3,2-b][1,4]oxazine-7-boronic acid, pinacol ester
CAS No.	910037-15-9
Molecular Formula	C14H19BN2O3
Molecular Weight	274.13 g/mol
Synonyms	4-Methyl-3,4-dihydro-2H-pyrido[3,2-b][1,4]oxazin-7-ylboronic acid pinacol ester; 7-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-4-methyl-3,4-dihydro-2H-pyrido[3,2-b][1,4]oxazine; 4-Methyl-2H-pyrido[3,2-b][1,4]oxazine-7-boronic acid pinacol ester; B-(4-Methyl-3,4-dihydro-2H-pyrido[3,2-b][1,4]oxazin-7-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 910037-15-9; Pinacol 4-methyl-3,4-dihydro-2H-pyrido[3,2-b][1,4]oxazine-7-boronate
EINECS	Contact for details

Quality Control

Our 4-Methyl-3,4-dihydro-2H-pyrido[3,2-b][1,4]oxazine-7-boronic acid, pinacol ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label or COA. The product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain optimal stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.