Description

2-(Tetrahydropyran-4-Yloxy)Pyridine-5-Boronic Acid, Pinacol Ester is a high-purity, protected boronic acid ester building block designed for advanced organic synthesis. This compound is critical for facilitating Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex carbon-carbon bonds. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate Synthesis: A key building block for constructing complex heterocyclic scaffolds found in drug discovery and development programs.
• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a stable, protected boronate reagent for the palladium-catalyzed formation of biaryl and other C-C bonds.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides requiring specific pyridine-based architectures.
• Material Science & OLED Development: Employed in the creation of organic electronic materials, ligands for catalysts, and advanced polymers.
• Academic & Contract Research: Essential for methodological studies and custom synthesis projects in university and CRO laboratories.

Basic Information

Product Name	2-(Tetrahydropyran-4-Yloxy)Pyridine-5-Boronic Acid, Pinacol Ester
CAS No.	910036-98-5
Molecular Formula	C16H24BNO4
Molecular Weight	305.18 g/mol
Synonyms	5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(tetrahydro-2H-pyran-4-yloxy)pyridine; 2-(Oxan-4-yloxy)pyridine-5-boronic acid pinacol ester; 2-(Tetrahydropyran-4-yloxy)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; THP-Protected Pyridine Boronic Ester; Pyridine-5-boronic acid, 2-(tetrahydro-2H-pyran-4-yloxy)-, 1,3,2-dioxaborolane ester; CAS 910036-98-5
EINECS	Contact for details

Quality Control

Every batch of 2-(Tetrahydropyran-4-Yloxy)Pyridine-5-Boronic Acid, Pinacol Ester is produced and analyzed under strict quality management protocols to ensure consistency and reliability for sensitive synthetic applications. Our products undergo rigorous quality testing, including HPLC, NMR, and mass spectrometry, to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity and identity are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.