Description

5-Fluoro-n-(1-([6-(Trifluoromethyl)Pyridin-3-Yl]Carbonyl)Piperidin-4-Yl)Indoline-1-Carboxamide is a high-purity, advanced pharmaceutical intermediate designed for research and development in modern drug discovery. This compound is critical for medicinal chemists seeking to develop novel therapeutic agents, particularly in oncology and central nervous system (CNS) disorders. It is primarily utilized by pharmaceutical R&D laboratories, biotechnology companies, and contract research organizations (CROs) for the synthesis of targeted small molecule candidates.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates targeting specific biological pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize potency and selectivity of lead compounds.
• Oncology Drug Development: Serves as a core scaffold for potential kinase inhibitors or other targeted cancer therapies.
• CNS Drug Discovery: Applied in the research of therapeutics for neurological and psychiatric conditions.
• Chemical Biology Probes: Utilized to create tool compounds for studying enzyme function and cellular signaling mechanisms.
• Preclinical Development: Supplies material for early-stage pharmacological and toxicological evaluation of new chemical entities.

Basic Information

Product Name	5-Fluoro-n-(1-([6-(Trifluoromethyl)Pyridin-3-Yl]Carbonyl)Piperidin-4-Yl)Indoline-1-Carboxamide
CAS No.	909662-07-3
Molecular Formula	C21H18F4N4O2
Molecular Weight	434.39 g/mol
Synonyms	5-Fluoro-N-[1-[[6-(trifluoromethyl)-3-pyridinyl]carbonyl]-4-piperidinyl]-2,3-dihydro-1H-indole-1-carboxamide; 5-Fluoro-N-(1-{[6-(trifluoromethyl)pyridine-3-carbonyl]piperidin-4-yl}indoline-1-carboxamide; 909662-07-3; UNII-7J9Y8F4U4N; 7J9Y8F4U4N; CHEMBL3186667; AKOS025147324; BDBM50388857
EINECS	Contact for details

Quality Control

Our 5-Fluoro-n-(1-([6-(Trifluoromethyl)Pyridin-3-Yl]Carbonyl)Piperidin-4-Yl)Indoline-1-Carboxamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client requirements for research and development purposes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.