Description

n-Methyl-4-(trifluoromethoxy)benzenesulfonamide is a specialized organofluorine sulfonamide derivative, a key building block in advanced chemical synthesis. Its molecular structure, featuring both a sulfonamide group and a trifluoromethoxy substituent, makes it a valuable intermediate for creating compounds with enhanced biological activity and physicochemical properties. This product is primarily utilized by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Research: Serves as a key building block for developing new herbicides, fungicides, and insecticides, where the trifluoromethoxy group can improve lipophilicity and metabolic stability.
• Material Science: Used in the research and development of advanced polymers and specialty materials where sulfonamide linkages and fluorine content are desired for specific thermal or chemical resistance properties.
• Chemical Synthesis: Acts as a versatile reagent for introducing the N-methylsulfonamide moiety into more complex molecular architectures in medicinal and process chemistry.
• Life Science Research: Employed as a reference standard or biochemical tool compound in academic and industrial research laboratories for method development and biological screening.

Basic Information

Product Name	n-Methyl-4-(trifluoromethoxy)benzenesulfonamide
CAS No.	909527-60-2
Molecular Formula	C8H8F3NO3S
Molecular Weight	255.21 g/mol
Synonyms	4-(Trifluoromethoxy)-N-methylbenzenesulfonamide; Benzenesulfonamide, 4-(trifluoromethoxy)-N-methyl-; N-Methyl-4-trifluoromethoxybenzenesulfonamide; 1-Methyl-4-(trifluoromethoxy)benzenesulfonamide; p-(Trifluoromethoxy)-N-methylbenzenesulfonamide; 909527-60-2; 4-(Trifluoromethoxy)-N-methylbenzene-1-sulfonamide
EINECS	Contact for details

Quality Control

Our n-Methyl-4-(trifluoromethoxy)benzenesulfonamide is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.