Description

2-[4-(tert-Butylsulfanyl)Phenyl]-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is a high-value organoboron building block, specifically a pinacol boronic ester derivative, essential for modern synthetic chemistry. Its core value lies in enabling the efficient construction of complex molecules through reliable cross-coupling reactions, such as the Suzuki-Miyaura reaction. This compound is critically needed by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for drug discovery, catalyst development, and the synthesis of functional organic molecules.

Application

• Pharmaceutical Intermediate: A key building block for synthesizing active pharmaceutical ingredients (APIs) and drug candidates via palladium-catalyzed cross-coupling reactions.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that require the incorporation of specific aryl-sulfide motifs.
• Material Science Research: Serves as a precursor for creating organic electronic materials, such as those used in OLEDs and organic photovoltaics, due to its functionalized aromatic core.
• Catalyst & Ligand Development: Employed in the synthesis of novel ligands and organometallic catalysts where the tert-butylthio group modulates electronic properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and bioconjugates for studying biological processes.
• Custom Synthesis & Contract Manufacturing: A critical reagent for custom synthesis houses and CROs/CMOs serving the global life sciences market.

Basic Information

Product Name	2-[4-(tert-Butylsulfanyl)Phenyl]-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No.	909255-87-4
Molecular Formula	C16H25BO2S
Molecular Weight	292.24 g/mol
Synonyms	4-(tert-Butylthio)phenylboronic acid pinacol ester; 4-(tert-Butylsulfanyl)benzeneboronic acid pinacol ester; [4-(tert-Butylthio)phenyl]boronic acid pinacol ester; 2-[4-(tert-Butylmercapto)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 4-(tert-Butylthiophenyl)boronic acid pinacol ester; Pinacol [4-(tert-butylthio)phenyl]boronate; 4-(tert-Butylsulfanyl)phenylboronic acid, pinacol ester
EINECS	Contact for details

Quality Control

Every batch of 2-[4-(tert-Butylsulfanyl)Phenyl]-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive applications like pharmaceutical R&D. A detailed Certificate of Analysis (COA) confirming identity, purity, and impurity profiles via HPLC, NMR, and other relevant techniques is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation and to minimize moisture uptake. Recommended storage temperature is 2-8°C for extended stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.