Description

4,4,5,5-Tetramethyl-2-[2-Methyl-5-(Methylsulfonyl)Phenyl]-1,3,2-Dioxaborolane is a high-purity, advanced boronic ester derivative, serving as a critical building block in modern synthetic organic chemistry. Its value lies in enabling efficient and selective cross-coupling reactions, which are fundamental for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for drug discovery and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides that require specific aryl-boronate functionalities.
• Organic Light-Emitting Diodes (OLEDs): Serves as a building block for creating electron-transport materials and emissive layer components in display technologies.
• Ligand and Catalyst Development: Employed in the research and production of novel ligands and organometallic catalysts for asymmetric synthesis.
• Polymer and Material Science: Facilitates the synthesis of specialty polymers, liquid crystals, and other functional materials with tailored properties.
• Chemical Biology & Proteomics: Utilized in the synthesis of molecular probes and activity-based protein profiling (ABPP) reagents.

Basic Information

Product Name	4,4,5,5-Tetramethyl-2-[2-Methyl-5-(Methylsulfonyl)Phenyl]-1,3,2-Dioxaborolane
CAS No.	909187-44-6
Molecular Formula	C15H23BO4S
Molecular Weight	310.22 g/mol
Synonyms	2-Methyl-5-(methylsulfonyl)phenylboronic acid pinacol ester; [2-Methyl-5-(methylsulfonyl)phenyl]boronic acid pinacol ester; 5-(Methylsulfonyl)-2-methylbenzeneboronic acid pinacol ester; 2-Methyl-5-(methylsulfonyl)phenylboronic acid, pinacol ester; 2-(2-Methyl-5-methanesulfonylphenyl)-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane; (2-Methyl-5-(methylsulfonyl)phenyl)boronic acid pinacol ester; 909187-44-6; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 4,4,5,5-Tetramethyl-2-[2-Methyl-5-(Methylsulfonyl)Phenyl]-1,3,2-Dioxaborolane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support cGMP and ISO standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.