Description

2-Methyl-2-(4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Propanoic Acid is a high-value, multi-functional pharmaceutical intermediate and organic building block featuring a protected boronic acid ester group. Its core value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone of modern medicinal chemistry for constructing complex biaryl structures. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-purity precursors for drug discovery and synthesis.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing biaryl motifs.
• Suzuki-Miyaura Cross-Coupling Reagent: Used in palladium-catalyzed coupling reactions to form carbon-carbon bonds between aryl groups, essential for creating complex organic molecules.
• Agrochemical Synthesis: Intermediate in the development of novel herbicides, fungicides, and insecticides that require specific aryl-boronate functionalities.
• Material Science Research: Precursor for organic electronic materials, such as polymers and small molecules used in OLEDs and organic photovoltaics.
• Chemical Biology & Proteomics: Can be utilized in the synthesis of chemical probes and affinity tags for studying protein function and interactions.
• Ligand Synthesis: Serves as a starting material for creating sophisticated ligands used in catalysis and metal-organic frameworks (MOFs).

Basic Information

Item	Details
Product Name	2-Methyl-2-(4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Propanoic Acid
CAS No.	909187-36-6
Molecular Formula	C16H23BO4
Molecular Weight	290.17 g/mol
Synonyms	2-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)-2-methylpropanoic acid; 2-Methyl-2-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]propionic acid; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-alpha,α-dimethylbenzeneacetic acid; Pinacol 2-(4-carboxy-2,2-dimethylpropyl)phenylboronate; 909187-36-6; BCPB Pinacol Ester
EINECS	Contact for details

Quality Control

Our 2-Methyl-2-(4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Propanoic Acid is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, suitable for sensitive applications like pharmaceutical R&D. All products undergo rigorous analytical testing, including HPLC, NMR, and MS, to verify identity and purity. Comprehensive Certificates of Analysis (COA) detailing all specifications are provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under inert atmosphere (e.g., nitrogen or argon) when appropriate to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.