Description

2-Methyl-5-Phenylthiophene-3-Boronic Acid is a high-value organoboron building block essential for modern synthetic chemistry. This compound matters as a key reagent in cross-coupling reactions, enabling the precise construction of complex molecular architectures. It is primarily needed by researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials industries for developing new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A critical precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used to create complex thiophene-containing molecules for new-generation herbicides, fungicides, and plant growth regulators.
• Organic Light-Emitting Diodes (OLEDs): Serves as a building block for electron-transport materials and emissive layer components in display and lighting technologies.
• Material Science Research: Employed in the development of conductive polymers, organic semiconductors, and metal-organic frameworks (MOFs).
• Chemical Biology & Proteomics: Utilized as a handle for bioconjugation and in the synthesis of molecular probes for target identification and validation.
• Catalyst Ligand Synthesis: Acts as a starting material for creating sophisticated ligands used in asymmetric catalysis and transition metal complexes.

Basic Information

Product Name	2-Methyl-5-Phenylthiophene-3-Boronic Acid
CAS No.	909103-23-7
Molecular Formula	C11H11BO2S
Molecular Weight	218.08 g/mol
Synonyms	(2-Methyl-5-phenylthiophen-3-yl)boronic acid; 2-Methyl-5-phenyl-3-thienylboronic acid; 5-Phenyl-2-methylthiophene-3-boronic acid; 3-Borono-2-methyl-5-phenylthiophene; Boronic acid, B-(2-methyl-5-phenyl-3-thienyl)-; 909103-23-7; 2-Methyl-5-phenylthiophene-3-boronic acid pinacol ester (common derivative)
EINECS	Contact for details

Quality Control

Our 2-Methyl-5-Phenylthiophene-3-Boronic Acid is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure compliance with exacting R&D and production standards. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) due to its hygroscopic and moisture-sensitive nature. Allow the container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥95% (Typical 97-99%)
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.