Description

2,5-Bis(4-Fluorophenyl)Thiophene-3-Carbonitrile is a high-value, multi-functional organic building block featuring a thiophene core flanked by fluorinated aromatic rings. This compound matters for its role as a key intermediate in the synthesis of advanced materials and active pharmaceutical ingredients, where its specific electronic and steric properties are critical. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and organic electronics industries for creating novel compounds with targeted functionalities.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of new-generation herbicides and pesticides, where the fluorine atoms enhance biological activity and metabolic stability.
• Organic Electronic Materials: Acts as a building block for organic semiconductors, hole-transport materials (HTMs), and non-fullerene acceptors in organic photovoltaics (OPVs) and OLEDs.
• Ligand and Catalyst Development: Employed in the design of specialized ligands for transition metal catalysis, facilitating challenging cross-coupling reactions.
• Fluorescent Probe and Dye Chemistry: The conjugated thiophene-fluorophenyl system is utilized in the creation of fluorescent tags and sensors for biochemical analysis.
• Academic and Industrial R&D: A valuable reagent for exploratory chemistry in universities and corporate research centers focusing on heterocyclic and fluorine chemistry.

Basic Information

Product Name	2,5-Bis(4-Fluorophenyl)Thiophene-3-Carbonitrile
CAS No.	908588-07-8
Molecular Formula	C17H9F2NS
Molecular Weight	297.32 g/mol
Synonyms	3-Cyano-2,5-bis(4-fluorophenyl)thiophene; 2,5-Di(4-fluorophenyl)-3-thiophenecarbonitrile; 2,5-Bis(p-fluorophenyl)thiophene-3-carbonitrile; 3-Thiophenecarbonitrile, 2,5-bis(4-fluorophenyl)-; 908588-07-8; AKOS005258555; BCP31962; FT-0773297
EINECS	Contact for details

Quality Control

Every batch of 2,5-Bis(4-Fluorophenyl)Thiophene-3-Carbonitrile undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our quality systems are designed to meet the stringent requirements of advanced R&D and scale-up processes. A comprehensive Certificate of Analysis (COA) detailing purity (typically by HPLC), identity confirmation (by IR, NMR), and impurity profile is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to prevent moisture absorption and contamination. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.