Description

4-(2-Pyridinyl)Phenylboronic Acid Pinacol Ester is a high-purity boronic ester derivative, a crucial protected intermediate in modern synthetic chemistry. Its value lies in its enhanced stability compared to the free boronic acid, facilitating handling and storage for complex cross-coupling reactions. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors developing novel active ingredients, particularly for Suzuki-Miyaura couplings.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, especially those containing biphenyl or heterobiaryl motifs.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides requiring specific aryl-aryl linkages.
• Material Science Research: Serves as a monomer or precursor in the development of organic electronic materials, such as OLEDs and conductive polymers.
• Ligand and Catalyst Development: Employed in the preparation of novel ligands for transition metal catalysts used in asymmetric synthesis.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and target engagement.
• Academic & Industrial R&D: A versatile reagent for method development and exploring new synthetic pathways in organic chemistry laboratories.

Basic Information

Product Name	4-(2-Pyridinyl)Phenylboronic Acid Pinacol Ester
CAS No.	908350-80-1
Molecular Formula	C₁₇H₂₀BNO₂
Molecular Weight	281.16 g/mol
Synonyms	2-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)pyridine; 4-(Pyridin-2-yl)phenylboronic Acid Pinacol Ester; 2-[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]pyridine; 4-(2-Pyridyl)phenylboronic Acid Pinacol Ester; 2-(4-Boronophenyl)pyridine Pinacol Ester; (4-(Pyridin-2-yl)phenyl)boronic Acid Pinacol Ester
EINECS	Contact for details

Quality Control

Our 4-(2-Pyridinyl)Phenylboronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.