Description

D-Ritalin Hydrochloride, (2R,2μr)-(+)-Threo-Methyl α-Phenyl-α-(2-Piperidyl)Acetate Hydrochloride is a high-purity, single-enantiomer form of methylphenidate hydrochloride, a central nervous system stimulant. This compound is critical for pharmaceutical research and development, offering a defined stereochemistry essential for studying specific pharmacological pathways and receptor interactions. It is primarily required by research institutions, analytical laboratories, and pharmaceutical companies engaged in neuroscience, drug discovery, and the development of enantiomerically pure active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Reference Standard: Serves as a certified standard for the quality control and analytical method validation of methylphenidate-based medications.
• Neuroscience Research: Used in preclinical studies to investigate the mechanisms of action, pharmacokinetics, and pharmacodynamics of CNS stimulants.
• Drug Discovery & Development: A key intermediate or starting material for the synthesis of novel therapeutic agents targeting attention deficit disorders and narcolepsy.
• Analytical Chemistry: Employed as a high-purity calibrant in chromatographic (HPLC, GC) and spectroscopic analyses to ensure accurate quantification.
• Metabolite Studies: Utilized in the synthesis and identification of specific metabolic products for toxicological and ADME (Absorption, Distribution, Metabolism, Excretion) profiling.
• Academic Research: Supports chemical and pharmacological education and research in university and institutional laboratories.

Basic Information

Product Name	D-Ritalin Hydrochloride, (2R,2μr)-(+)-Threo-Methyl α-Phenyl-α-(2-Piperidyl)Acetate Hydrochloride
CAS No.	907200-07-1
Molecular Formula	C14H19NO2·HCl
Molecular Weight	269.77 g/mol (Free base) / 306.23 g/mol (Hydrochloride salt)
Synonyms	(+)-threo-Methylphenidate hydrochloride; d-threo-Methylphenidate HCl; (2R,2'R)-(+)-threo-Methylphenidate hydrochloride; Dexmethylphenidate hydrochloride; d-Methylphenidate hydrochloride; Focalin impurity; (R,R)-Methylphenidate hydrochloride; α-Phenyl-α-(2-piperidyl)acetic acid methyl ester hydrochloride
EINECS	Contact for details

Quality Control

Our D-Ritalin Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets stringent specifications for research and development purposes. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and impurity profiles as determined by HPLC, NMR, and other relevant pharmacopeial methods.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0% (on anhydrous basis)
Chiral Purity (Enantiomeric Excess)	≥99.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤2.0%; Any single impurity ≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.