Description

(S)-Tomoxetine is the single enantiomer of tomoxetine, a selective norepinephrine reuptake inhibitor (NRI) of high pharmaceutical significance. This compound is the active pharmaceutical ingredient (API) in medications used to treat attention deficit hyperactivity disorder (ADHD). It is essential for pharmaceutical manufacturers and research institutions engaged in the development and production of enantiomerically pure neuropharmacological agents. The material is supplied with a focus on high purity and consistency to meet stringent regulatory requirements.

Application

• Active Pharmaceutical Ingredient (API): Primary use in the formulation of prescription medications for the treatment of Attention Deficit Hyperactivity Disorder (ADHD).
• Pharmaceutical Research & Development: Serves as a critical reference standard and building block in neuropharmacology studies and the development of new therapeutic agents.
• Analytical Standard: Used in quality control laboratories for method development, validation, and assay calibration in HPLC and other chromatographic systems.
• Process Chemistry: Employed in the scale-up and optimization of synthetic routes for enantiomerically pure pharmaceuticals.
• Metabolite Studies: Utilized in preclinical and clinical research to understand drug metabolism and pharmacokinetics.

Basic Information

Product Name	(S)-Tomoxetine
CAS No.	105314-53-2
Molecular Formula	C17H21NO
Molecular Weight	255.36 g/mol
Synonyms	(S)-(-)-Tomoxetine; (S)-N-Methyl-3-phenyl-3-(o-tolyloxy)propylamine; (S)-Methylphenethylamine Derivative; (S)-LY139603; Atomoxetine Impurity; (S)-Tomoxetine Hydrochloride (Salt Form Precursor); L-Tomoxetine
EINECS	Contact for details

Quality Control

Every batch of (S)-Tomoxetine is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including chiral purity analysis, to ensure compliance with pharmaceutical-grade standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.5%
Chiral Purity (Enantiomeric Excess)	≥99.0%
Related Substances (HPLC)	Total impurities ≤1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.