Description

2-Thiophen Potassiumtrifluoroborate is an organoboron reagent belonging to the potassium trifluoroborate salt family, a highly valuable class of compounds in modern synthetic chemistry. Its core value lies in its enhanced stability and handling properties compared to traditional boronic acids, making it a superior building block for robust cross-coupling reactions. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries who require reliable, high-purity intermediates for constructing complex molecular architectures.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds between the thiophene moiety and aryl or vinyl halides, crucial for synthesizing biaryl and heterobiaryl structures.
• Pharmaceutical Intermediate Synthesis: Used in the research and development of active pharmaceutical ingredients (APIs), particularly those containing thiophene heterocycles for various therapeutic applications.
• Agrochemical Compound Development: Serves as a building block for creating novel herbicides, fungicides, and insecticides that incorporate the thiophene ring system.
• Material Science and Organic Electronics: A precursor for synthesizing conjugated polymers and small molecules used in organic light-emitting diodes (OLEDs), organic photovoltaics (OPVs), and semiconductors.
• Ligand and Catalyst Preparation: Employed in the synthesis of specialized ligands and organometallic catalysts that utilize thiophene-based frameworks.
• Chemical Biology and Medicinal Chemistry: Facilitates the creation of molecular probes and tool compounds for target identification and validation in drug discovery programs.

Basic Information

Product Name	2-Thiophen Potassiumtrifluoroborate
CAS No.	906674-55-3
Molecular Formula	C4H3BF3KS
Molecular Weight	185.99 g/mol
Synonyms	Potassium 2-Thienyltrifluoroborate; 2-Thienyl Potassium Trifluoroborate; 2-Thienyltrifluoroborate Potassium Salt; Potassium (Thiophen-2-yl)trifluoroborate; 2-Thiophene Potassium Trifluoroborate; 2-Thienyl-BF3K; Thiophen-2-yltrifluoroboronic Acid Potassium Salt
EINECS	Contact for details

Quality Control

Our 2-Thiophen Potassiumtrifluoroborate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including NMR (1H, 11B, 13C) and HPLC analysis, to confirm identity and purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for advanced intermediates, supporting our customers in regulated development environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Recommended long-term storage temperature is 2-8°C (refrigerated). Allow the sealed container to equilibrate to room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
11B NMR Purity	≥ 95.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.