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3-Methoxy-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenol CAS NO 906008-22-8


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CAS No.:906008-22-8

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

3-Methoxy-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenol is a high-purity boronic ester derivative, a critical building block in modern synthetic chemistry. Its value lies in its dual functionality, serving as a protected phenol and a versatile boronate ester for Suzuki-Miyaura cross-coupling reactions. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for complex molecule synthesis.

Application

  • Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules containing substituted phenol and aryl boronate motifs.
  • Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides that require specific aromatic coupling steps.
  • Liquid Crystal & OLED Materials: Serves as a building block for advanced electronic materials, where precise molecular architecture is crucial for performance.
  • Polymer & Resin Chemistry: Employed in the development of specialty polymers and high-performance resins through controlled polymerization or functionalization.
  • Chemical Research & Development: A valuable reagent for medicinal chemistry and process chemistry R&D, enabling the exploration of new chemical spaces.
  • Cross-Coupling Reactions: Primarily utilized in palladium-catalyzed Suzuki-Miyaura cross-couplings to form biaryl and other carbon-carbon bonds efficiently.

Basic Information

Item Detail
Product Name 3-Methoxy-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenol
CAS No. 906008-22-8
Molecular Formula C13H19BO4
Molecular Weight 250.10 g/mol
Synonyms 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3-methoxyphenol; 3-Hydroxy-5-methoxyphenylboronic acid pinacol ester; 3-Methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzenol; 5-Methoxy-3-hydroxyphenylboronic acid pinacol ester; (3-Hydroxy-5-methoxyphenyl)boronic acid pinacol ester; 906008-22-8; Phenol, 3-methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-
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Quality Control

Our 3-Methoxy-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) detailing all specifications are provided with each shipment to guarantee traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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