Description

2-(4-tert-Butylphenyl)-5,5-Dimethyl-1,3,2-Dioxaborinane is a high-purity, organoboron reagent widely used in advanced organic synthesis. This compound is valued for its stability and reactivity as a key building block in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is essential for R&D and production in the pharmaceutical, agrochemical, and materials science industries, where precise and reliable boron chemistry is required.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A critical boron reagent for forming carbon-carbon bonds in the synthesis of biaryl compounds, a common motif in active pharmaceutical ingredients (APIs) and organic electronic materials.
• Pharmaceutical Intermediate Synthesis: Serves as a key precursor in the development of novel drug candidates, particularly those containing substituted biphenyl or terphenyl structures.
• Agrochemical Manufacturing: Used in the synthesis of advanced herbicides, fungicides, and insecticides that require specific aryl-boron intermediates.
• Materials Science & OLED Development: Employed in the creation of organic light-emitting diode (OLED) materials and other advanced polymers where controlled aryl incorporation is necessary.
• Ligand and Catalyst Preparation: Acts as a starting material for synthesizing specialized ligands and organometallic catalysts used in homogeneous catalysis.
• Academic and Industrial R&D: A valuable tool for chemists in research laboratories exploring new synthetic methodologies and compound libraries.

Basic Information

Product Name	2-(4-tert-Butylphenyl)-5,5-Dimethyl-1,3,2-Dioxaborinane
CAS No.	905966-37-2
Molecular Formula	C16H25BO2
Molecular Weight	260.18 g/mol
Synonyms	4-tert-Butylphenylboronic acid 5,5-dimethyl-1,3,2-dioxaborinane ester; 2-(4-(tert-Butyl)phenyl)-5,5-dimethyl-1,3,2-dioxaborinane; (4-(tert-Butyl)phenyl)boronic acid cyclic ester with neopentyl glycol; 5,5-Dimethyl-2-[4-(1,1-dimethylethyl)phenyl]-1,3,2-dioxaborinane; 4-tert-Butylbenzeneboronic acid neopentyl glycol ester; Neopentyl glycol (4-tert-butylphenyl)boronate
EINECS	Contact for details

Quality Control

Our 2-(4-tert-Butylphenyl)-5,5-Dimethyl-1,3,2-Dioxaborinane is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including NMR, HPLC, and GC analysis, to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged storage or when opening the container to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.