Description

Ethyl 3-Bromo-2-Oxo-3-(4-(Trifluoromethyl)Phenyl)Propanoate is a high-value brominated ketoester building block featuring a trifluoromethylphenyl group. This compound is critical for the synthesis of complex molecules, offering a versatile handle for further functionalization in medicinal chemistry and advanced material science. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for constructing complex heterocycles and bioactive molecules.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Material Science Research: Serves as a precursor for specialty polymers and advanced organic electronic materials due to its unique electronic properties.
• Chemical Biology Probes: Employed in the synthesis of labeled compounds and molecular probes for studying biological mechanisms.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Item	Detail
Product Name	Ethyl 3-Bromo-2-Oxo-3-(4-(Trifluoromethyl)Phenyl)Propanoate
CAS No.	905807-87-6
Molecular Formula	C₁₂H₁₀BrF₃O₃
Molecular Weight	339.11 g/mol
Synonyms	Ethyl 3-Bromo-2-oxo-3-[4-(trifluoromethyl)phenyl]propanoate; 3-Bromo-2-oxo-3-(4-(trifluoromethyl)phenyl)propanoic Acid Ethyl Ester; Ethyl α-Bromo-β-oxo-4-(trifluoromethyl)hydrocinnamate; 905807-87-6; Ethyl 3-bromo-2-oxo-3-(p-trifluoromethylphenyl)propionate
EINECS	Contact for details

Quality Control

Our Ethyl 3-Bromo-2-Oxo-3-(4-(Trifluoromethyl)Phenyl)Propanoate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency suitable for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container must be kept tightly closed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.