Description

1-Hydroxy-1,3-Dihydrobenzo[C][1,2]Oxaborole-5-Carbonitrile is a high-value, heterocyclic organic compound featuring a unique benzoxaborole core integrated with a nitrile functional group. This molecular architecture makes it a critical advanced pharmaceutical intermediate and a versatile building block for the synthesis of novel bioactive molecules. It is primarily utilized by research institutions and chemical manufacturers in the pharmaceutical, agrochemical, and material science sectors for developing new therapeutic agents and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of boron-containing drug candidates, particularly for antiviral, antifungal, and anti-inflammatory applications.
• Agrochemical Research: Used as a building block for developing new herbicides, fungicides, and insecticides with novel modes of action.
• Material Science: Employed in the research and development of organic electronic materials, sensors, and polymers due to its electron-deficient aromatic system.
• Chemical Synthesis: Acts as a versatile synthon for constructing complex heterocyclic frameworks through various coupling and cyclization reactions.
• Bioconjugation & Probe Development: Utilized in medicinal chemistry for creating molecular probes and bioconjugates, leveraging the reactivity of the boronic acid derivative and nitrile group.

Basic Information

Item	Details
Product Name	1-Hydroxy-1,3-Dihydrobenzo[C][1,2]Oxaborole-5-Carbonitrile
CAS No.	905710-80-7
Molecular Formula	C8H6BNO2
Molecular Weight	158.95 g/mol
Synonyms	5-Cyano-1-hydroxy-1,3-dihydro-2,1-benzoxaborole; 1-Hydroxy-1,3-dihydrobenzo[c][1,2]oxaborole-5-carbonitrile; 5-Cyanobenzoxaborol-1-ol; Benzoxaborole-5-carbonitrile, 1-hydroxy-1,3-dihydro-; 1-Hydroxy-5-cyanobenzoxaborole; 905710-80-7; 1,3-Dihydro-1-hydroxybenzo[c][1,2]oxaborole-5-carbonitrile
EINECS	Contact for details

Quality Control

Our production of 1-Hydroxy-1,3-Dihydrobenzo[C][1,2]Oxaborole-5-Carbonitrile adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment. We support cGMP compliance for pharmaceutical applications, and specifications can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when appropriate to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.