Description

1-Chloro-6-Fluoronaphthalene is a halogenated naphthalene derivative serving as a versatile and high-value synthetic intermediate. Its molecular structure, featuring both chlorine and fluorine substituents, makes it a critical building block for introducing specific electronic and steric properties into advanced materials and active pharmaceutical ingredients. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and organic electronics sectors who require precise, high-purity intermediates for complex synthesis.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for fluorinated drug candidates targeting CNS disorders and oncology.
• Agrochemical Synthesis: Building block for developing advanced pesticides and herbicides, where the fluorine atom enhances biological activity and environmental stability.
• Organic Light-Emitting Diodes (OLEDs): Used in the research and production of electron-transport materials and host materials for efficient OLED displays and lighting.
• Liquid Crystal Materials: Intermediate for creating fluorinated components in liquid crystal mixtures, improving the performance of LCDs.
• Organic Semiconductor Research: Serves as a core structure in the development of n-type semiconductors and other organic electronic materials.
• Cross-Coupling Reactions: Valuable substrate in Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to construct complex biaryl systems.
• Fluorine Chemistry Research: A standard reagent for studying structure-activity relationships and the effects of halogen substitution in organic synthesis.

Basic Information

Product Name	1-Chloro-6-Fluoronaphthalene
CAS No.	904923-95-1
Molecular Formula	C₁₀H₆ClF
Molecular Weight	180.60 g/mol
Synonyms	6-Fluoro-1-chloronaphthalene; 1-Chloro-6-fluoronaphthalene; Naphthalene, 1-chloro-6-fluoro-; 1-Chloro-6-fluoro-naphthalene; 904923-95-1; 6-Fluoro-1-chloro-naphthalene
EINECS	Contact for details

Quality Control

Our 1-Chloro-6-Fluoronaphthalene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment ensures the material meets the stringent requirements for research and commercial synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.