Description

2-Chloro-1-Fluoro-4-(4-Nitrophenyl)Benzene is a specialized halogenated aromatic building block of significant interest in advanced organic synthesis. Its precise molecular architecture, featuring chloro, fluoro, and nitrophenyl substituents, makes it a valuable intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for candidates requiring halogenated biphenyl or diphenyl ether scaffolds.
• Agrochemical Synthesis: Serves as a precursor in the creation of advanced herbicides, fungicides, and insecticides, where the nitro group can be further functionalized.
• Liquid Crystal & OLED Materials: Used in the synthesis of specialized organic electronic materials, where its rigid, polar structure can influence mesogenic or emissive properties.
• Polymer Chemistry: Acts as a monomer or cross-linking agent for producing high-performance polymers with enhanced thermal stability and chemical resistance.
• Organic Synthesis Research: Employed in academic and industrial R&D for Suzuki, Sonogashira, and other cross-coupling reactions to create complex polyaromatic systems.
• Dye & Pigment Intermediate: Utilized in the development of specialized azo dyes and pigments, leveraging the nitro group for chromophore formation.

Basic Information

Product Name	2-Chloro-1-Fluoro-4-(4-Nitrophenyl)Benzene
CAS No.	904325-90-2
Molecular Formula	C12H7ClFNO2
Molecular Weight	251.64 g/mol
Synonyms	1-Chloro-2-fluoro-4-(4-nitrophenyl)benzene; 4-(2-Chloro-5-fluorophenyl)nitrobenzene; 2-Chloro-5-fluoro-4'-nitrobiphenyl; 4-Nitro-2'-chloro-5'-fluorobiphenyl; (2-Chloro-5-fluorophenyl)(4-nitrophenyl); [1,1'-Biphenyl]-4-carbonitrile, 2-chloro-5-fluoro-4'-nitro-; 904325-90-2
EINECS	Contact for details

Quality Control

Our 2-Chloro-1-Fluoro-4-(4-Nitrophenyl)Benzene is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical quality attributes. Our commitment to reliable supply and traceable documentation supports your R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.