Description

4H-1-Benzopyran-4-One, 6,7-Difluoro- is a high-purity fluorinated chromone derivative, a key advanced intermediate in modern organic synthesis. Its value lies in its unique difluoro-substituted benzopyranone scaffold, which is crucial for modulating the biological activity and physicochemical properties of target molecules. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a critical building block for the synthesis of fluorinated drug candidates, particularly in oncology, CNS, and anti-infective therapeutic areas.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and pesticides where the difluoro motif enhances stability and bioavailability.
• Material Science: Acts as a precursor for synthesizing specialized fluorinated organic compounds used in OLED materials, liquid crystals, and polymers.
• Chemical Biology & Proteomics: Employed as a scaffold or tag in the design of molecular probes and enzyme inhibitors for biochemical research.
• Academic & R&D: Utilized in universities and contract research organizations (CROs) for methodological studies in fluorination chemistry and heterocyclic compound synthesis.

Basic Information

Product Name	4H-1-Benzopyran-4-One, 6,7-Difluoro-
CAS No.	904318-79-2
Molecular Formula	C9H4F2O2
Molecular Weight	182.13 g/mol
Synonyms	6,7-Difluorochromone; 6,7-Difluoro-4H-chromen-4-one; 6,7-Difluoro-1-benzopyran-4-one; 6,7-Difluoro-4H-1-benzopyran-4-one; Chromone, 6,7-difluoro-; 6,7-Difluoro-4-chromone; 4H-Chromen-4-one, 6,7-difluoro-
EINECS	Contact for details

Quality Control

Our 4H-1-Benzopyran-4-One, 6,7-Difluoro- is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.