Description

3-Chloro-4-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzoic Acid is a high-value boronic ester derivative, serving as a critical building block in modern synthetic chemistry. Its core value lies in enabling efficient carbon-carbon bond formation via the Suzuki-Miyaura cross-coupling reaction, a cornerstone for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise, scalable intermediates for active ingredient and functional material synthesis.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those containing biaryl or substituted benzoic acid motifs.
• Agrochemical Synthesis: Used to create novel herbicides, fungicides, and insecticides through palladium-catalyzed cross-coupling reactions.
• Liquid Crystal & OLED Material Production: Acts as a building block for constructing complex organic molecules used in display and lighting technologies.
• Polymer & Specialty Chemical Manufacturing: Enables the incorporation of functional aromatic units into polymers and other advanced materials.
• Chemical Research & Development: A versatile reagent for academic and industrial R&D labs exploring new synthetic pathways and novel compounds.
• Diagnostic Reagent Synthesis: Used in the development of probes and sensors that rely on specific boronic acid-diol interactions.

Basic Information

Product Name	3-Chloro-4-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzoic Acid
CAS No.	904310-72-1
Molecular Formula	C₁₃H₁₆BClO₄
Molecular Weight	282.52 g/mol
Synonyms	3-Chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoic Acid; 2-(3-Chloro-4-carboxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 4-Carboxy-2-chlorophenylboronic Acid Pinacol Ester; 3-Chloro-4-borono-benzoic Acid Pinacol Ester; Benzoic acid, 3-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; 904310-72-1; 3-Chloro-4-(pinacolatoboryl)benzoic Acid
EINECS	Contact for details

Quality Control

Our 3-Chloro-4-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzoic Acid is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specification parameters. Our quality commitment supports compliance with cGMP, ISO, and other relevant regulatory frameworks for intermediate manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.